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Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement
By inhibiting NNMT, research suggests that 5-Amino-1MQ may help enhance NAD+ availability, which has downstream implications in metabolic health and mitochondrial function
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In fact, studies show that up to 33% of Crohns disease patients are B12 deficient compared to just 16% of people with ulcerative colitis