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By stopping FOXO4 from holding onto p53, it enables p53 to perform its functionremove senescent cells through apoptosis

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This makes retinol particularly effective for texture, pigmentation, fine lines from photodamage, and acne

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*Correspondence: Li-Chen Gao, [email protected] This article was submitted to Pharmacology of Anti-Cancer Drugs, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Our genes have built-in mechanisms to prevent these genetic errors, but sometimes they fail