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Sermorelin tends to produce a steady rise in IGF-1 (insulin-like growth factor 1) within the age-appropriate range, improving sleep quality, recovery, and body composition with a low risk of side effects, says Candice Knight, M.D., a longevity-focused board-certified physician in Family and Integrative Medicine

Crucially: all AEs (with the exception of transient urticarial rashes) were more common at higher doses (125 or 250 mcg/kg) which is precisely why the authors singled out 30 and 60 mcg/kg as the better-tolerated doses

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Rights and permissions Oncogenesis is an open-access journal published by Nature Publishing Group

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