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A blockage of ascorbate accumulation in response to high light was also observed when glutathione deficiency was induced pharmacologically by buthionine sulfoximine treatment, providing extra evidence that, in high-light conditions, glutathione acts as a substitute for ascorbate reduction (Figure 1)

doi: 10.1016/j.immuni.2024.08.003

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It took a week or so for the angry rash to go away, but my skin texture changed