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This phenomenon also leads to an increase in metabolic intermediates for the biosynthesis of inflammatory and degradative proteins, which in turn activate key transcription factors and inflammatory signalling pathways involved in catabolic processes, and the persistent perpetuation of drivers of pathogenesis

S11b, c)

N., & Venn, B

Most malignant cells rely on glucose metabolism through aerobic glycolysis, the so-called Warburg effect, with a sharp increase in glucose uptake and lactate production (Lin et al., 2020)

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