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[11] Two other meta-analyses reported a similar decrease in relative risk
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A 2021 randomized controlled trial published in Diabetes Care (N=105) compared dulaglutide 1.5 mg weekly against glimepiride over 24 weeks in adults with type 2 diabetes and found that dulaglutide significantly reduced plasma malondialdehyde (a lipid peroxidation marker) and raised superoxide dismutase activity
These findings align with recent randomized clinical trials showing that (GLP-1 drugs), especially tirzepatide, improved obstructive sleep apnea severity, potentially through weight loss and metabolic or respiratory mechanisms, wrote the team led by senior researcher Yong Chen, a professor of biostatistics at the University of Pennsylvanias Perelman School of Medicine in Philadelphia
Peer review Peer review information Nature Medicine thanks Naveed Sattar and the other, anonymous, reviewer(s) for their contribution to the peer review of this work