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Toxicology 350352 , 4048 (2016)

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

While metformin can cross the BBB, it has poor solubility and its brain concentration is low to induce sufficient neuroprotective action 19,67

Four-Week Toxicity Study of Phenyl Isotiocyanate in Rats

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We must not discount caffeine as a compound that has pharmacological properties