The human equivalent dose of approximately 0.035 mg is extremely small, suggesting that even standard anti-aging doses could provide some degree of neurological benefit as a secondary effect
Even the risk of mortality from accidents is elevated among the overweight population
In humans, homozygous loss-of-function mutations in the ICK gene cause endocrine-cerebro-osteodysplasia syndrome, an autosomal recessive ciliopathy showing neonatal lethality with various developmental defects involving the endocrine, cerebral, and skeletal systems, and short rib-polydactyly syndrome, an autosomal recessive ciliopathy characterized by perinatal lethality with short ribs, shortened and hypoplastic long bones, polydactyly, and multiorgan system abnormalities (46, 47, 48)
This is the larger of the two, covering gastroparesis (stomach paralysis), ileus (bowel obstruction), and related severe GI injuries
On its own, GLP-1 does several useful things
GCL is the rate-limiting enzyme in synthesis of glutathione from cysteine, and is the enzyme inhibited by BSO