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Description

Physiol Rev 98(4):2381-2430

In addition it enables the body to rid itself of unwanted toxins and heavy metals, detoxifying the liver, the bodys most concentrated source of glutathione

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In ALS, cytosolic TDP-43 translocated into mitochondria via TOM20, triggering ROS production and mitochondrial DNA (mtDNA) release through the mitochondrial permeability transition pore (mPTP)