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Preclinical studies showed no adverse effects across several organ systems including liver, spleen, lung, kidney, brain, thymus, prostate, and ovaries in studies up to 6 weeks

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Similarly, both study designs were double-blind, randomized, and placebo-controlled, but while the first study had two arms parallel-design (control and test), the second was a crossover, with two cycles of 12 weeks for each treatment, Placebo and Eriomin

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First, we tested whether microbial structures including bacterial muramyl dipeptide (MDP) and lipopolysaccharide (LPS) or the pro-inflammatory cytokines interferon (IFN) and TNF would induce GLP-1 secretion ( Figure 3A )