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The fourth row in Table 4 requires more comment

In one sentence, the mechanism is receptor-mediated: GHRP binding to GHS-R1a activates a Gq/11-coupled phospholipase C cascade that mobilises intracellular calcium and triggers exocytosis of stored GH from the anterior pituitary, independent of hypothalamic GHRH signalling

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In dense cultures, disrupting lactate production revealed its key role in reshaping DC functions, leading to increased production of interleukin-12 (IL-12) and decreased interleukin-10 (IL-10)

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