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Oral administration of HGSD (100 mg/kg) significantly improved glucose and lipid metabolism in diabetic rats compared with pure BBR (100 mg/kg), BBR tablets (100 mg/kg), or metformin (300 mg/kg),this related to the inhibition of iPLA2/p38 MAPK pathway to decrease -cell apoptosis (Zhaojie et al., 2014)

Rachel Nania is an award-winning health editor and writer at AARP.org, who covers a range of topics including diseases and treatments.

This research was also partially supported by the Intellectual and Developmental Disabilities Research Center (1U54 HD083092) at Baylor College of Medicine

Hierarchical clustering of rows and columns was performed using the complete linkage algorithm with the Euclidean distance metric

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