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Realizing their full potential requires an interdisciplinary strategy to overcome these translational barriers and integrate phytochemicals into modern treatment paradigms

By utilizing virtual screening techniques, we have successfully conducted a comprehensive screening of a natural compound known as Urolithin A (UA), which exhibits remarkable inhibition of osteoblastic ferroptosis while simultaneously promoting the process of osteogenesis through its precise targeting mechanism on GPX4

doi: 10.1038/aps.2017.207 211 MarventanoSKolaczPCastellanoSGalvanoFBuscemiSMistrettaAet al

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J Exp Zoology 258, 14350

Measurement of phosphatidylserine (PS) Annexins are a group of proteins that bind to phospholipids (preferably PS) and their binding depends on calcium