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Protein binding is 75%

For patients at moderate risk of rhabdomyolysis who are at low risk of fluid overload, consider empiric IV fluid administration (e.g., D5LR at 150 ml/hr)

Common weekly titration schedule A common once-daily schedule starts at 0.6 mg for the first week, then moves to 1.2 mg, 1.8 mg, 2.4 mg, and 3 mg in weekly steps

During rapid weight loss, the body may temporarily redirect nutrients and energy toward essential organs and bodily functions instead of hair growth

Briefly, urine metabolites were purified using Discovery C18 SPE cartridges (SPE 96 well plate, 100 mg/well, 2 ml)

J Appl Microbiol (2022) 132(3):157396