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MT-1 is a linear tridecapeptide preferentially activating MC1R and producing predominantly peripheral pigmentation and photoprotection biology with minimal central melanocortin receptor effects at research doses

The "evidence base" column is a deliberate honesty check: it flags how much of each estimate rests on preclinical work versus human observation

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Cancer Letters, 183 (1), 1-8

The compound was well tolerated with no evidence of genotoxicity, indicating its potential as a therapeutic agent for type 2 diabetes and obesity in humans

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