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Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: the step 4 randomized clinical trial

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Ipamorelin is a selective pentapeptide agonist of the ghrelin receptor (GHS-R1a), studied for growth hormone secretagogue activity with a preclinical profile suggesting minimal impact on cortisol, prolactin, or appetite signaling relative to earlier-generation GHRPs