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Both mechanisms increase cytoplasmic concentrations of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), producing a cytoplasmic surge of monoamines

Insoluble fiber: Whole grains, nuts, and vegetables like broccoli and cauliflower add bulk to promote regular bowel movements

Their comparison illustrates the two dominant strategies in modern obesity pharmacotherapy: combination therapy with proven agents versus novel single-molecule multi-agonism

Additionally, older people suffering from acute ischemic stroke were found to be deficient for riboflavin (118), and riboflavin deficiency has been linked to a higher risk of fracture in postmenopausal women with the MTHFR 677T variant (119)

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