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An increase in the -KG/succinic acid ratio can promote the activation of M2 macrophages [24]

This study investigates the release and cytotoxicity of two anticancer drugs from the MESH system, highlighting the importance of drug solubility, interaction with the polymeric matrix, and nanoparticle formulation on drug release and efficacy, and demonstrating the promise of combination polymeric matrices as suitable replacements of Gliadel for sustained drug delivery in GBM patients

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In healthy individuals without cancer, the peptides promote normal healing processes

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