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Alterations in xenobiotic metabolism in the long-lived Little mice

SUPPLEMENTS: Calcium (from Dicalcium Phosphate), Phosphorus (from Dicalcium Phosphate), L-Glutathione

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Second, the arginine at position 3 in the native sequence was substituted with leucine (hence R3)

Overall, Nrf2 is fundamental for the sustenance of the GSH redox state through glutathione reductase transcriptional regulation and for cell protection against oxidative stress (Harvey et al., 2009)

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