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"Given the significant risk of bias present in the majority of the included trials, further well-designed and comprehensive RCTs with larger sample sizes and robust analytical methods are needed to more accurately determine the influence of L-carnitine on cardiovascular disease (CVD) risk factors in individuals with diabetes and glucose intolerance," the researchers concluded
Conclusions and Future Perspectives The collective evidence positions incretin receptor agonists as a unique class of drugs with multi-organ anti-fibrotic potential, now extending to fibro-inflammatory diseases like osteoarthritis
GLP-1 agonists carry the strongest clinical evidence for PCOS improving insulin sensitivity, reducing androgens, and supporting weight regulation
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