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Limitations: RGN-259 pending FDA approval, not yet commercially available

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In Figure 3, we delineate the hypothetical mechanism of the GHGHRIGF1 axis, which may be mostly mediated by IGF1, on the regulation of mitochondrial biogenesis, mitophagy, and mitochondrial function based on the results of studies in the recent decades

Annulus fibrosus cell phenotypes in homeostasis and injury: implications for regenerative strategies

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