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In addition to the overall analysis on the efficacy and safety outcomes mentioned above, we also focused on the effects of the different classes of drugs as add-ons to monotherapy and the treatment duration on HbA1c, body weight, FPG and SBP, which provided a high level of evidence on the efficacy and safety of GLP-1RA/SGLT-2i combination therapy versus monotherapy in patients with T2DM

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Although transcriptional analysis of AITC-treated seedlings revealed down-regulation of many auxin-inducible genes, auxin marker lines exposed to AITC did not indicate a change in auxin response and auxin-resistant mutants did not reveal an altered resistance to AITC 74

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