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The unbound fraction of semaglutide was calculated as the semaglutide concentration in the supernatant when incubated with immobilised HSA divided by the same for the reference

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All data were subjected to one-way analysis of variance (ANOVA) (two-way ANOVA was applied to analyze data of blood glucose level at different time points before/after SAH) followed by multiple comparisons between groups using Tukeys post hoc test and represented as mean SD

Like Ozempic, Wegovy is taken as a once-weekly injection, but it delivers a higher dose of semaglutide