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Anforth R, Carlos G, Clements A, Kefford R, Fernandez-Peas P

When telomeres shorten to a critical size, the cell grows old, which causes aging as we know it

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It is, for instance, significantly shorter-lasting than sildenafil approximately 2-3 hours versus 4-5 hours9 15 16 which itself has a relatively short duration of efficacy

developed a PKM2 allosteric converter (PAC) comprising three functional modules: (1) an allosteric effector module featuring a serine-based motif that bound to PKM2 at Leu-353 and Asp-354, inducing dimer-to-tetramer conversion

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