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Peripherally administered GLP-1R agonists may also act directly on GLP-1R at other sites in the brain, notably circumventricular organs and some hypothalamic regions with fenestrated capillaries (101103)

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U54HD061221), which is a part of the National Institutes of Health (NIH) Rare Disease Clinical Research Network (RDCRN), supported through collaboration between the Office of Rare Diseases Research (ORDR), the National Center for Advancing Translational Science (NCATS) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and NIH K08DK106453

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