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GST-Pns11 or GST-Pelo was incubated with glutathione-Sepharose beads (Amersham, 17-0756-01) for 5 h at 4 C, centrifuged for 5 min at 500 g , and then the supernatant was discarded

Depression: A meta-analysis of 5 RCTs (n=574) found that NAC significantly improved depressive symptoms, particularly in individuals with high baseline symptom severity (Fernandes et al., J Clin Psychiatry, 2016) [73]

Financial support was provided by the Wellcome Trust Core Award Grant Number 203141/Z/16/Z

SNPs in SUOX act as a block (especially if combined with the faster CBS SNP) and may result in a log jam of sulfites, causing reactions

Statistical significance was assessed by ordinary One-Way ANOVA followed by Dunnetts multiple comparisons test in b , c , d

In vitro inhibition of human placental glutathione S -transferase by 3-arylcoumarin derivatives