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It is important to emphasize that speed is only helpful if the patient can maintain it

Notably, when liposomes were incubated with both SNX1 and SNX2, spherical vesicles were frequently observed alongside tubular structures, closely resembling the formation of spherical vesicles near MVBs observed in vivo

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Escalation of doses should be paused once grade 2 nausea or vomiting develops, as continued dose increases at this stage increases the risk of intolerance and discontinuation