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Metabolism Clinical and Experimental Journal 2010;59:1190-1199

In the New England Journal of Medicine a double-blind randomized trial of 156 participants with early Parkinsons disease were assigned to lixisenatide or placebo

This weight loss can lead to improved overall health outcomes, reducing the risk of complications associated with diabetes, such as cardiovascular disease and neuropathy

Plus, we won't know the long term side effects for quite some time...like what we're seeing today with SSRI's and tardive dyskinesia

A 2025 review on the effects of weight cycling on muscle and sarcopenia suggested that it may lead to disproportionate fat regain, reduced FFM, accelerated age-related muscle loss and an increased risk for functional impairment and disability, particularly in older or frail individuals, contributing to worsened muscle health outcomes including sarcopenic obesity [14]

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