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Despite the new class of GLP-1 agonists, there remain only 5 FDA-approved medications to treat obesity, highlighting a clear need for additional pharmacotherapy

Key differences: exogenous GH suppresses endogenous GH production through negative feedback (IGF-1 hypothalamus), while ipamorelin does not

doi:10.1007/s11095-015-1652-z

All animals were bred in the pathogen-free facility with a 12 h light/dark cycle at temperature (2025 C), relative humidity (4060%), and had ad libitum access to food and water

I would rather know early, because correcting B12 deficiency takes time