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Limitations include the paucity of larger and long-term RCTs in populations with T1D and particularly studies investigating newer, weekly GLP-1 and GLP-1/GIP RAs

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However, as of March 2026, Hers claims it has shifted its focus to FDA-approved weight-loss treatments, limiting compounded semaglutide to medical necessity

doi:10.1186/s12876-020-01356-2 47

The certification process includes mass spectrometry analysis to confirm the exact amino acid sequence of BPC-157