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The Lamtor1 construct includes sequence for a TEV-cleavable GST tag at the N terminus, followed by sequence for a His 6 tag, which replaces its first seven residues

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Both trials demonstrated twice daily oral doses of nerandomilast (9 mg and 18 mg) significantly reduced the decline in forced vital capacity (FVC) from baseline at week 52, compared to placebo (adjusted mean change from baseline in FVC: FIBRONEER-IPF, -138.6 mL with nerandomilast 9 mg, -114.7 mL with nerandomilast 18 mg, -183.5 mL with placebo

Present study was approved by Institutional Ethics Committee of the Iran University of Medical Sciences (Approval ID: IR.IUMS.FMD.REC.1398.090)

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