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The GLP-1 receptor activation reduces appetite through direct signaling to the hypothalamus, slows gastric emptying so food stays in the stomach longer, and enhances insulin secretion

10.1186/s12933-025-02614-x 106 WardR

Abstract Background Sodiumglucose transporters 2 inhibitors (SGLT-2i) and glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are recommended along with metformin for the potential cardiovascular benefits among type 2 diabetes

It works as an appetite suppressant, helping to reduce hunger and increase feelings of fullness

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Additionally, compared to the tumors of mice without drug treatment and those treated with Ru(II)-OH (64.4%) and NP2 (73.6%), the tumors of mice treated with NP4 (81.2%) exhibited a higher proportion of mature DCs (CD80 + CD86 + ) (Supplementary Fig