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[70] It turns out that this test can often uncover a thyroid issue much earlier than the typical thyroid test (for TSH levels alone) will

doi: 10.1038/srep12404 47 YunM-KNourseAWhiteSWRockCOHeathRJ

Berthoud, H

The result at week 88: Continued tirzepatide: :Lost an additional 5.5% of body weight (total loss from baseline: ~25%) Switched to placebo: Regained 14.0% of body weight (net loss from baseline: ~9%) A 19-point swing between continued and discontinued groups

BOTTOM LINE: Those at greatest risk of vitamin B12 deficiency are vegans and vegetarians, who get little to no B12 from the diet

This is similar to how high blood pressure or diabetes medications work if the medication is treating a chronic condition, stopping it typically reverses the benefit