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445,446 Although the mechanisms related to lipid metabolism in liver regeneration have not been fully elucidated, several potential targets deserve further consideration (Fig

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Ginsenoside Rg1 downregulates calpain-1 to inhibit STAT3 phosphorylation, blocks the IL-6/STAT3 inflammatory pathway and the release of inflammatory factors, and can inhibit the activation of the TXNIP/NLRP3 inflammasome, reducing IL-1 secretion (Zhang R

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3a) Consistent with a deleterious role for free iron in ASCVD, ApoE-/- mice exposed to chronic iron overload displayed exacerbated atherosclerosis likely secondary to VEC damage or death, which was attenuated by dietary iron restriction or iron chelation 62,63

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Materials and methods In this study, we carried out data analysis of differentially expressed genes (DEGs) of 26,966 probe sets (p.s.) from Affymetrix MoGene 1.0 ST microarray data from mouse mucosa scrapings produced in our previous study (15)

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