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The sorted cells were washed twice with 50 mL phosphate-buffered saline to remove the FreSHtracer and then further cultivated in culture medium for 24 h prior to in vitro or in vivo experiments, as described below
The subsequent success of GLP-1 receptor agonists, despite early gastrointestinal intolerance and safety concerns, illustrates how such signals may be manageable through improved formulation and dosing rather than indicative of fundamental biological unsuitability
Fukao T, et al
Clinical outcomes may vary due to individual biological differences
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Whilst these medications are not licensed specifically for dyslipidaemia treatment, clinical trials show reductions in total cholesterol, LDL cholesterol, and triglycerides alongside their primary metabolic benefits
