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Magnesium glycinate is typically considered to be safe to use alongside GLP-1 medications such as semaglutide or tirzepatide. Our expert says GLP-1 users have been consistently identified as at risk of micronutrient deficiencies, including magnesium deficiency, so it is paramount to discuss this possibility with the physician who prescribed the meds

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If the vial may have frozen: discard it

Tirzepatide may offer similar protection by lowering inflammation that contributes to joint destruction in arthritis

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Patients receiving both medications should be closely monitored for electrolyte imbalance and signs of toxicity, with regular assessment of serum potassium and Digoxin levels