In the normal situation (without increased oxidative stress), 90% of glucose is catabolized anaerobically to pyruvate or lactate by the direct glycolytic pathway, or EMP
10.1016/j.clnu.2007.05.007 34
Evid.-Based Ment
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But it should be noted that at meantime of brain protection, BBB also excludes more than 98% of small-molecule drugs and all macromolecular therapeutics from access to the brain
Secondly, conflicting effects are presented in PCD pathways
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