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doi: 10.1038/s41392-025-02255-2, 39

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Why Do GLP-1 Medications Trigger Hair Thinning

Through the glutathione redox cycle, reduced glutathione (GSH) is converted to its oxidized form (GSSG) and then recycled back to its active state, helping maintain the cellular environment required for normal protein function, DNA integrity, and metabolic activity

Topical 5% NAC gel applied twice daily for 8 weeks reduced comedones by 37-46% compared to 23% with placebo [55]

Medication initiation, monitoring of side effects, and dose titration can be performed through an online video consultation , which is especially important during the first weeks while the effective therapeutic dose is being reached