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These factors do not necessarily preclude treatment but require discussion with healthcare providers

due to their immunosuppressive effects, PIs have demonstrated substantial potential in the development of drugs for inflammation, carcinoma, immune disorders, and muscular dystrophies 25, 26

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However, the absence of large-scale human clinical trials is a genuine limitation

It is administered as a once-weekly subcutaneous injection and belongs to a novel class of medications known as dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists

Diabetes Care 2015;38:3442