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Phosphatidylinositol (4,5)-bisphosphate (PIP2) is hydrolyzed to generate the second messengers inositol trisphosphate (IP3) and diacylglycerol (DAG), which regulate intracellular calcium levels and activate Protein Kinase C (PKC), respectively

The FDA position on expired medications (and why biologics are different) The FDA takes a clear position: do not use medications past their expiration dates

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Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury