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Albuterol selectively binds receptors on bronchial smooth muscle, activating Gs-proteincoupled adenylyl cyclase and increasing intracellular cyclic AMP (cAMP)

Protein levels of p53 are regulated through its ubiquitination by the E3 ubiquitin ligase, murine double minute 2 (MDM2)

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Hence, mutation of either C168 or C190 results in the loss of the redox responsiveness of GSAAT1 in planta