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Differential effect of dietary selenium on the long-term neurotoxicity induced by MDMA in mice and rats

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Glutathione might inhibit the effects of cerebral infarction and enhance antiapoptotic signaling after ischemic stroke, suggesting that GSH may be a potent therapeutic antioxidant that can attenuate severe pathologies after ischemic stroke, and stimulating GSH synthesis through administration of GSH precursors and micronutrients like selenium can optimize GSH and GSH peroxidase for optimal antioxidant defense in cerebral ischemia (155, 156)

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Hepatic NF-B activity was determined by measuring both NF-B-DNA-binding activity using nuclear proteins and the expression of NF-B target genes