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Idrees et al

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summaries how lactate accumulation and lactylation can suppress cytotoxic T cells and favor regulatory T cells through metabolic acidification, GAPDH-dependent translational control and NFAT inhibition, yet under certain conditions lactate oxidation in T cells can support memory formation and long-term antitumor responses [25]

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A researcher or clinician who understands this will neither dismiss the peptide outright nor promote it as a proven therapy both errors ignore where the data actually sit

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