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Strategies for IGF delivery to chondrocytes and cartilage matrix are essential for its clinical application in OA treatment

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Although both drugs were extensively studied before approval, semaglutide has only been on the market since 2017 and tirzepatide since 2022

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Where the oral route is not deemed adequate, initial treatment similar to that for patients with pernicious anemia may be indicated depending on the severity of the deficiency

One of the most important defense we have against any disease is our gut microbiome, which is constantly assaulted by a range of toxins, parasites, bacteria and fungi that we inevitably ingest