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For many patients, headaches diminish or resolve completely as treatment continues and the body adjusts to the medication

Figure 12

Another network meta-analysis using a Cochrane Librarybased web search found 16 randomized controlled trials used to create a frequentist network meta-analysis for people with type 2 diabetes to compare GLP1-RA (before the FLOW study, described in what follows), SGLT2i, and MRA classes compared with placebo on a background of good metabolic management and RAASi

Both medications share similar gastrointestinal side effects: nausea, diarrhea, vomiting, and decreased appetite

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