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Short-term use, as in gout, generally much better tolerated than long-term use

Vitamin C works in synergy with glutathione to support normal collagen formation, while L-cysteine is an important nutrient involved in the bodys natural glutathione production

As a control, a solution of HBSS supplemented with 2 mM Gln was used

184 PacielloF.RinaudoM.LongoV.CoccoS.ConfortoG.PisaniA.et al (2021)

Matrix-related gene activity

To assess how acute SNIP1 depletion impacts pre-mRNA splicing, we performed total RNA-seq on nuclear extracts from HCT116 dTAG SNIP1 cells treated with either 500 nM dTAG-v1 or the DMSO control for 4 h