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This interaction induces dimerization of intracytoplasmic TIR domains, which in turn induces binding of adaptor protein MyD88 via its own TIR domain (93)

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Cagrilintide (AM833) Cagrilintide is a long-acting amylin analog designed for once-weekly (OW) SC administration (based on the structure of natural amylin), developed by Novo Nordisk [112]

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