2.2 Mechanism-Enhancing Modifications (Albumin Binding, Half-Life Extension) A fatty acid side chain facilitates reversible albumin binding
The most common side effects are gastrointestinal (think: constipation, diarrhea, or an upset stomach)
Additionally, rapid weight loss associated with these medications might sometimes precipitate headaches through various metabolic changes, though this mechanism requires further study
The variable presentation often leads to diagnostic delays, with many patients experiencing symptoms for years before diagnosis
This was a retrospective study of electronic medical records, meaning the researchers were limited in their ability to establish causation between semaglutide/tirzepatide-type weight loss medication prescription and alcohol intoxication and opioid poisoning events in patients with alcohol and opioid use disorder
Mild side effects, especially the day after injection, are still possible but usually less intense than the initial titration step