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Excess Fe 2+ accumulates within the cell, leading to the formation of unstable iron clusters

Studies have demonstrated that the coordinated activation of the ROS/PI3K/Akt and Wnt/-catenin signaling pathways can induce the expression of HIF-1, driving glycolysis-centered metabolic reprogramming

The maximum dose in a single day or infusion is usually around 500-1,000 mg in clinical research settings

In: Autophagy: Biology and Diseases

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