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Glutathione: The Skin Brightening Antioxidant Why It Works Glutathione is an antioxidant that interferes with the synthesis of melanin in the skin and, in fact, drives the conversion to production of the lighter-colored (pheomelanin) versus the darker-colored (eumelanin) types of melanin, it combats reactive species in the skin, thereby putting a damper on hyperpigmentation

A 2020 review in Journal of Physiology and Pharmacology called for multi-center, GLP-compliant studies to verify the Zagreb group's findings 15

c) BHMT: The third possibility for this step takes place almost exclusively in the liver